Enalapril (marketed as Vasotec in the US, Enaladex and Renitec in some other countries, and Enacard for veterinary use) is an angiotensin-converting-enzyme (ACE) inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure.ACE converts the peptide hormone angiotensin I to angiotensin II. One of the actions of angiotensin II is the vasoconstriction of blood vessels, resulting in an increase in blood pressure.

Property Value
dbo:abstract
  • Enalapril (marketed as Vasotec in the US, Enaladex and Renitec in some other countries, and Enacard for veterinary use) is an angiotensin-converting-enzyme (ACE) inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure.ACE converts the peptide hormone angiotensin I to angiotensin II. One of the actions of angiotensin II is the vasoconstriction of blood vessels, resulting in an increase in blood pressure. ACE inhibitors such as enalapril prevent this effect. Enalapril has been shown to lower the death rate in systolic heart failure.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. (en)
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  • DB00584
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  • (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid (Diagrams above are enalapril and enalaprilat, respectively. Data below refers to enalapril unless indicated) (en)
  • (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid (en)
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  • 2016-09-07 18:02:24 (xsd:date)
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  • 2016-04-25 04:51:09 (xsd:date)
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  • DB00584 (en)
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dbp:excretion
  • renal (en)
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  • 28 (xsd:integer)
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  • Enalapril VanDerVals transparent.png (en)
  • Enalapril ball-and-stick model.png (en)
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  • I.V. and P.O. (en)
  • intravenous and by mouth (en)
  • by mouth (en)
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  • Vasotec, Renitec (en)
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  • Enalapril (marketed as Vasotec in the US, Enaladex and Renitec in some other countries, and Enacard for veterinary use) is an angiotensin-converting-enzyme (ACE) inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure.ACE converts the peptide hormone angiotensin I to angiotensin II. One of the actions of angiotensin II is the vasoconstriction of blood vessels, resulting in an increase in blood pressure. (en)
rdfs:label
  • Enalapril (en)
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