This HTML5 document contains 22 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

PrefixNamespace IRI
dcthttp://purl.org/dc/terms/
dbohttp://dbpedia.org/ontology/
foafhttp://xmlns.com/foaf/0.1/
dbthttp://dbpedia.org/resource/Template:
rdfshttp://www.w3.org/2000/01/rdf-schema#
n7http://en.wikipedia.org/w/index.php?title=WAY-214156&oldid=
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://dbpedia.org/resource/Category:Selective_ER%CE%B2
wikipedia-enhttp://en.wikipedia.org/wiki/
dbchttp://dbpedia.org/resource/Category:
dbphttp://dbpedia.org/property/
xsdhhttp://www.w3.org/2001/XMLSchema#
dbrhttp://dbpedia.org/resource/
n11http://en.wikipedia.org/w/index.php?title=WAY-214156&action=
Subject Item
dbr:WAY-214156
foaf:isPrimaryTopicOf
wikipedia-en:WAY-214156
rdfs:comment
WAY-214156 is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It is 100-fold selective for the ERβ over the ERα with an IC50 of 4.2 nM (compare to estradiol with IC50 values of ~3–4 nM for both the ERα and ERβ). The drug is less selective for the ERβ than is prinaberel (ERB-041, WAY-202041), another selective ERβ agonist, but is more potent in comparison. WAY-214156 may produce anti-inflammatory effects via the ERβ and has been proposed as a potential treatment for inflammatory conditions such as rheumatoid arthritis.
rdfs:label
WAY-214156
dbo:abstract
WAY-214156 is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It is 100-fold selective for the ERβ over the ERα with an IC50 of 4.2 nM (compare to estradiol with IC50 values of ~3–4 nM for both the ERα and ERβ). The drug is less selective for the ERβ than is prinaberel (ERB-041, WAY-202041), another selective ERβ agonist, but is more potent in comparison. WAY-214156 may produce anti-inflammatory effects via the ERβ and has been proposed as a potential treatment for inflammatory conditions such as rheumatoid arthritis.
dbo:wikiPageEditLink
n11:edit
dbo:wikiPageExtracted
2019-06-20T09:49:32Z
dbo:wikiPageHistoryLink
n11:history
dbo:wikiPageID
52624984
dbo:wikiPageLength
3607
dbo:wikiPageModified
2019-06-15T16:18:43Z
dbo:wikiPageOutDegree
23
dbo:wikiPageRevisionID
901975346
dbo:wikiPageRevisionLink
n7:901975346
dbp:wikiPageUsesTemplate
dbt:Estrogen_receptor_modulators dbt:Genito-urinary-drug-stub dbt:Drugbox dbt:Reflist
dct:subject
n5:_agonists dbc:Nitriles dbc:Phenols dbc:Synthetic_estrogens
Subject Item
wikipedia-en:WAY-214156
foaf:primaryTopic
dbr:WAY-214156